APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Neat |
Note :
FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.
|
Not tested in other applications.
Calculated MW
Product Note
This antibody binds to both glycoforms of human CD43 (Kyoizumi et al. 2004)
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA, 5% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KG-1 cells.
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Phycoerythrin (PE)
RRID
AB_377279
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
sialophorin , CD43 , GALGP , GPL115 , LSN
Cellular Localization
Membrane
Background
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Database
Research Area
DATA IMAGES
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GTX76311 FACS Image
FACS analysis of human peripheral blood lymphocytes using GTX76311 CD43 antibody [DFT-1] (PE).
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REFERENCE
There are currently no references for CD43 antibody [DFT-1] (PE) (GTX76311). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD43 antibody [DFT-1] (PE) (GTX76311). Be the first to share your experience with this product.