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CD45 antibody [HI30] (PE)

Anti-CD45 antibody [HI30] (PE) used in Flow cytometry (FACS). GTX00526-08

Cat. No. GTX00526-08

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 HI30

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
100 test ($209)
See all CD45 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 5 μl/1x105-1x108 cells

Note :

FACS
The suggested use of these reagents is in a final volume of 100μl.
Not tested in other applications.

Calculated MW

147 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM NaH₂PO₄, 150mM NaCl, 0.1% gelatin

Preservative

0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.025 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-CD45 antibody [HI30] (PE) used in Flow cytometry (FACS). GTX00526-08

GTX00526-08 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX00526-08 CD45 antibody [HI30] (PE).
Solid line : Primary antibody
Dashed line : Mouse IgG1 isotype control (PE)
Antibody amount : 0.125 μg

REFERENCE

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REVIEW

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Package List Price ($)
$ 209