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CD63 antibody [NKI/C3 (MX-49.129.5)]

Anti-CD63 antibody [NKI/C3 (MX-49.129.5)] used in IHC (Paraffin sections) (IHC-P). GTX21318

Cat. No. GTX21318

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 NKI/C3 (MX-49.129.5)

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($449)
See all CD63 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100‐1:200

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Smooth plasma membrane fraction of MeWo cells.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD63 molecule , LAMP-3 , ME491 , MLA1 , OMA81H , TSPAN30

Cellular Localization

Cell membrane , Lysosome membrane

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES

Anti-CD63 antibody [NKI/C3 (MX-49.129.5)] used in IHC (Paraffin sections) (IHC-P). GTX21318

GTX21318 IHC-P Image

IHC-P analysis of human melanoma tissue using GTX21318 CD63 antibody [NK1/C3NKI/C3 (MX-49.129.5)].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 449