APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1/500 - 1/2000 |
1/200 - 1/1000 |
1/200 - 1/1000 |
1/200 - 1/400 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human CDK5 expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cyclin dependent kinase 5 , LIS7 , PSSALRE
Background
This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Database
Research Area
DATA IMAGES
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GTX60441 ELISA Image
ELISA analysis of antigen using GTX60441 CDK5 antibody [4E4].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng
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GTX60441 FACS Image
FACS analysis of K562 cells using GTX60441 CDK5 antibody [4E4]. Green : CDK5 Purple : negative control
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GTX60441 IHC-P Image
IHC-P analysis of human cerebellum tissue (left) and brain tissue (right) using GTX60441 CDK5 antibody [4E4].
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GTX60441 ICC/IF Image
ICC/IF analysis of GC7901 cells using GTX60441 CDK5 antibody [4E4]. Green : CDK5 Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments
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GTX60441 WB Image
WB analysis of HeLa (1), K562 (2), PC-12 (3) and Cos7 (4) cell lysate using GTX60441 CDK5 antibody [4E4].
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REFERENCE
There are currently no references for CDK5 antibody [4E4] (GTX60441). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CDK5 antibody [4E4] (GTX60441). Be the first to share your experience with this product.