APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 16 - 32 μg/ml |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Gibbon, Gorilla(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 19 amino acid peptide from C-terminus of human CELSR1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cadherin EGF LAG seven-pass G-type receptor 1 , ADGRC1 , CDHF9 , CELSR1 , FMI2 , HFMI2 , ME2 , cadherin EGF LAG sevenpass Gtype receptor 1
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX13169 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX13169 CELSR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 8.4 μg/ml
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GTX13169 IHC-P Image
IHC-P analysis of human testis tissue using GTX13169 CELSR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 8.4 μg/ml
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GTX13169 IHC-P Image
IHC-P analysis of human adrenal tissue using GTX13169 CELSR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 8.4 μg/ml
|
REFERENCE
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REVIEW
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