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CHRFAM7A antibody

Anti-CHRFAM7A antibody used in IHC (Paraffin sections) (IHC-P). GTX55571
Anti-CHRFAM7A antibody used in IHC (Paraffin sections) (IHC-P). GTX55571

Cat. No. GTX55571

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all CHRFAM7A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50 - 1:200
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion , CHRNA7 , CHRNA7-DR1 , D-10 , NACHRA7

Cellular Localization

Membrane,Cell membrane; Multi-pass membrane protein

Background

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CHRFAM7A antibody used in IHC (Paraffin sections) (IHC-P). GTX55571

GTX55571 IHC-P Image

IHC-P analysis of human prostate tissue using GTX55571 CHRFAM7A antibody.
Dilution : 1:100

Anti-CHRFAM7A antibody used in IHC (Paraffin sections) (IHC-P). GTX55571

GTX55571 IHC-P Image

IHC-P analysis of human stomach tissue using GTX55571 CHRFAM7A antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399