APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| 5μg/ml |
Not tested in other applications.
Calculated MW
Positive Control
The peptide used to generate this antibody is available for purchase (GTX89157-PEP).
Predict Reactivity
Mouse, Rat, Sheep, Bovine, Dog(>80% identity)
PROPERTIES
Form
Liquid
Buffer
TBS, 0.5% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide with sequence KLYYDNEKCWFGKR, from the internal region of the protein sequence according to NP_004373.2.
Purification
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
corticotropin releasing hormone receptor 1 , CRF-R , CRF-R-1 , CRF-R1 , CRF1 , CRFR-1 , CRFR1 , CRH-R-1 , CRH-R1 , CRHR , CRHR1L
Cellular Localization
Cell membrane; Multi-pass membrane protein , Endosome
Background
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016]
Database
Research Area
DATA IMAGES
|
GTX89157 IHC-P Image
IHC-P analysis of human cortex using GTX89157 CRHR1 (aa 250 - 263) antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml
|
REFERENCE
There are currently no references for CRHR1 (aa 250 - 263) antibody, Internal (GTX89157). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CRHR1 (aa 250 - 263) antibody, Internal (GTX89157). Be the first to share your experience with this product.
