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CTRP4 antibody

Anti-CTRP4 antibody used in Western Blot (WB). GTX85503
Anti-CTRP4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85503
Anti-CTRP4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85503

Cat. No. GTX85503

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all CTRP4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 4 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918) , Rat Brain Tissue Lysate(GTX27942)

Product Note

These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CTRP4 antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP4.The immunogen is located within amino acids 90 - 140 of CTRP4.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C1q and TNF related 4 , CTRP4 , ZACRP4

Cellular Localization

Secreted

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of mouse CTRP4 have been reported.

Database

Research Area

DATA IMAGES

Anti-CTRP4 antibody used in Western Blot (WB). GTX85503

GTX85503 WB Image

WB analysis of rat brain tissue lysate using GTX85503 CTRP4 antibody.
Working concentration : (A) 1, (B) 2, and (C) 4 μg/ml

Anti-CTRP4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85503

GTX85503 IHC-P Image

IHC-P analysis of human brain tissue using GTX85503 CTRP4 antibody.
Working concentration : 20 μg/ml

Anti-CTRP4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85503

GTX85503 IHC-P Image

IHC-P analysis of human brain tissue using GTX85503 CTRP4 antibody.
Working concentration : 10 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399