APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 16 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rabbit, Bovine, Hamster, Pig, Bat, Chimpanzee, Elephant, Gorilla, Horse, Marmoset, Orangutan(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 17 amino acid peptide from C-terminus of human CXCR6.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_424883
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
BONZO,CD186,CXC motif chemokine receptor 6,CXCR6,STRL33,TYMSTR,Bonzo,Chemokine Receptor 6,C-X-C motif chemokine receptor 6
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
Database
Research Area
DATA IMAGES
|
GTX77935 IHC-P Image
IHC-P analysis of human tonsil, interfollicular zone tissue using GTX77935 CXCR6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
REFERENCE
There are currently no references for CXCR6 antibody (GTX77935). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CXCR6 antibody (GTX77935). Be the first to share your experience with this product.
