GeneTex

  • Country / Location Selection

United States (US)

CYP46A1 antibody

Overexpression
Anti-CYP46A1 antibody used in Western Blot (WB). GTX30682
Anti-CYP46A1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30682
Anti-CYP46A1 antibody used in Western Blot (WB). GTX30682
Anti-CYP46A1 antibody used in Western Blot (WB). GTX30682

Cat. No. GTX30682

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Rabbit
Package
100 μl ($419)
See all CYP46A1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:500
IHC-P 1:200
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse samples.

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to residues between 200-250 of human CYP46A1. [UniProt# Q9Y6A2]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytochrome P450 family 46 subfamily A member 1 , CP46 , CYP46

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-CYP46A1 antibody used in Western Blot (WB). GTX30682

GTX30682 WB Image

WB analysis of transfected 293 cells using GTX30682 CYP46A1 antibody.

Anti-CYP46A1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30682

GTX30682 ICC/IF Image

ICC/IF analysis of SH-SY5Y cells using GTX30682 CYP46A1 antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI

Anti-CYP46A1 antibody used in Western Blot (WB). GTX30682

GTX30682 WB Image

Overexpression

WB analysis of HEK293 mock (Lane 1) or overexpressing CYP46A1 (Lane 2) cell lysate using GTX30682 CYP46A1 antibody.

Anti-CYP46A1 antibody used in Western Blot (WB). GTX30682

GTX30682 WB Image

WB analysis of human brain tissue lysate using GTX30682 CYP46A1 antibody.

REFERENCE

There are currently no references for CYP46A1 antibody (GTX30682). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CYP46A1 antibody (GTX30682). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 419