GeneTex

  • Country / Location Selection

United States (US)

CYP46A1 antibody

Anti-CYP46A1 antibody used in Western Blot (WB). GTX65985
Anti-CYP46A1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65985

Cat. No. GTX65985

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CYP46A1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 24-280 of human CYP46A1 (NP_006659.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytochrome P450 family 46 subfamily A member 1 , CP46 , CYP46

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CYP46A1 antibody used in Western Blot (WB). GTX65985

GTX65985 WB Image

WB analysis of various sample lysates using GTX65985 CYP46A1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CYP46A1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65985

GTX65985 IHC-P Image

IHC-P analysis of human prostate tissue using GTX65985 CYP46A1 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for CYP46A1 antibody (GTX65985). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CYP46A1 antibody (GTX65985). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399