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Cathelicidin antibody

Anti-Cathelicidin antibody used in Western Blot (WB). GTX85418
Anti-Cathelicidin antibody used in IHC (Paraffin sections) (IHC-P). GTX85418
Anti-Cathelicidin antibody used in IHC (Paraffin sections) (IHC-P). GTX85418
Anti-Cathelicidin antibody used in IHC (Paraffin sections) (IHC-P). GTX85418

Cat. No. GTX85418

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all Cathelicidin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Cathelicidin.The immunogen is located within amino acids 50 - 100 of Cathelicidin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cathelicidin antimicrobial peptide , CAP-18 , CAP18 , CRAMP , FALL-39 , FALL39 , HSD26 , LL37

Cellular Localization

Secreted

Background

One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

Database

Research Area

DATA IMAGES

Anti-Cathelicidin antibody used in Western Blot (WB). GTX85418

GTX85418 WB Image

WB analysis of human spleen tissue lysate using GTX85418 Cathelicidin antibody.
Working concentration : 1 μg/ml

Anti-Cathelicidin antibody used in IHC (Paraffin sections) (IHC-P). GTX85418

GTX85418 IHC-P Image

IHC-P analysis of human spleen tissue using GTX85418 Cathelicidin antibody.
Working concentration : 5 μg/ml

Anti-Cathelicidin antibody used in IHC (Paraffin sections) (IHC-P). GTX85418

GTX85418 IHC-P Image

IHC-P analysis of human spleen tissue using GTX85418 Cathelicidin antibody.
Working concentration : 5 μg/ml

Anti-Cathelicidin antibody used in IHC (Paraffin sections) (IHC-P). GTX85418

GTX85418 IHC-P Image

IHC-P analysis of human spleen tissue using GTX85418 Cathelicidin antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399