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Cav1.1 antibody

Anti-Cav1.1 antibody used in IHC (Paraffin sections) (IHC-P). GTX16634
Anti-Cav1.1 antibody used in Western Blot (WB). GTX16634

Cat. No. GTX16634

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all Cav1.1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

210 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.85 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide CGNVDPDESARIS, corresponding to amino acid residues 506-518 (2nd  extracellular loop, domain IV) of rat CaV1.1 (Accession  : Q02485).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

calcium voltage-gated channel subunit alpha1 S , Cchl1a3 , RGD1565743

Background

skeletal isoform and subunit of voltage dependent L-type Ca+2 channel; may mediate renal Ca+2 reabsorption; may play a role in bone metabolism [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Cav1.1 antibody used in IHC (Paraffin sections) (IHC-P). GTX16634

GTX16634 IHC-P Image

IHC-P analysis of rat skeletal muscle tissue using GTX16634 Cav1.1 antibody. CACNA1S  staining is highly specific for striated muscle cells. Note that smooth muscle cells of arteries are not stained (arrow). Hematoxilin is used as the counterstain.
Dilution : 1:100

Anti-Cav1.1 antibody used in Western Blot (WB). GTX16634

GTX16634 WB Image

WB analysis of rat skeletal muscle lysate using GTX16634 Cav1.1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

Application Reference

Osuru HP et al. Front Cardiovasc Med 2022; 9 : 711421 Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.
Kumar RA et al. J Physiol 2020; 598 (19) : 4357-4369 Dietary nitrate supplementation increases diaphragm peak power in old mice.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639