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Caveolin 1 antibody [4D6]

Anti-Caveolin 1 antibody [4D6] used in IHC (Paraffin sections) (IHC-P). GTX01969

Cat. No. GTX01969

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4D6

Isotype

 IgG2a

Application

 WB, IHC-P

Reactivity

 Human
Package
500 μl ($519)
See all Caveolin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:4000
IHC-P 1:200

Note :

IHC-P
High temperature antigen unmasking technique. Standard ABC technique.
Not tested in other applications.

Calculated MW

20 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to the N-terminus domain of the human caveolin-1 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caveolin 1 , BSCL3 , CGL3 , LCCNS , MSTP085 , PPH3 , VIP21

Background

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-Caveolin 1 antibody [4D6] used in IHC (Paraffin sections) (IHC-P). GTX01969

GTX01969 IHC-P Image

IHC-P analysis of normal human colon tissue using GTX01969 Caveolin 1 antibody [4D6]. Note cytoplasmic staining of smooth muscle and endothelium.

REFERENCE

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REVIEW

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Package List Price ($)
$ 519