APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 - 1:2000 |
1:100 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein of human CLDN3
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C7orf1 , CLDN3 , CPER2 , CPETR2 , HRVP1 , RVP1 , claudin 3 , Claudin 3
Cellular Localization
Cell junction,Tight junction,Cell membrane
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX00665 IHC-P Image
IHC-P analysis of mouse stomach tissue using GTX00665 Claudin 3 antibody.
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GTX00665 IHC-P Image
IHC-P analysis of human stomach tissue using GTX00665 Claudin 3 antibody.
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GTX00665 WB Image
WB analysis of various sample lysates using GTX00665 Claudin 3 antibody. Dilution : 1:400 Loading : 25μg per lane
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GTX00665 IHC-P Image
IHC-P analysis of human colon tissue using GTX00665 Claudin 3 antibody.
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REFERENCE
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REVIEW
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