GeneTex
United States (US)

Claudin 4 antibody [C2C3], C-term

GTX108483_WB_19011507_784.jpg

Cat No. GTX108483

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Positive Control

HCT116

Predict Reactivity

Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human claudin 4. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Claudin 4,Cpe-R,Cper,Cpetr,Cpetr1,Wbscr8,Hcpe-R,Cldn4

Cellular Localization

Cell junction , tight junction , Cell membrane; Multi-pass membrane protein , Cell junction , tight junction , Cell membrane

Background

This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX108483_WB_19011507_784.jpg

GTX108483 WB Image

Sample (30 ug of whole cell lysate)
A: HCT116 12% SDS PAGE
GTX108483 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf