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Claudin 8 antibody, Internal

Anti-Claudin 8 antibody, Internal used in Flow cytometry (FACS). GTX80481
Anti-Claudin 8 antibody, Internal used in Western Blot (WB). GTX80481

Cat. No. GTX80481

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, FACS

Reactivity

 Human
Package
400 μl ($399)
See all Claudin 8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 140-166 amino acids from the Central region of human CLDN8.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

claudin 8 , HEL-S-79

Cellular Localization

Cell membrane

Background

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Claudin 8 antibody, Internal used in Flow cytometry (FACS). GTX80481

GTX80481 FACS Image

FACS analysis of 293 cells using GTX80481 Claudin 8 antibody, Internal.
Green : primary antibody
Blue : negative control

Anti-Claudin 8 antibody, Internal used in Western Blot (WB). GTX80481

GTX80481 WB Image

WB analysis of 293 cell lysate (35ug/lane) using GTX80481 Claudin 8 antibody, Internal.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399