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DCD antibody [G-81]

Cat. No. GTX54428

Host

Mouse

Clonality

Monoclonal

Clone Name

G-81

Isotype

IgM

Application

WB, IHC-P, ELISA

Reactivity

Human
Package
100 μg ($399)
PRODUCT

Summary

The monoclonal antibody G-81 is useful as a immunohistochemical tool to find the tumour cells that differentiate towards eccrine secretory cells in cutaneous mixed tumours. Furthermore, the antibody can be used for the detection of biochemical and histochemical changes of the sweat gland in the healing process of wound.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Fractioned sweat peptides in complete Freund's adjuvant

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AIDD,DCD,DCD1,DSEP,HCAP,PIF,dermcidin,Dermcidin

Cellular Localization

Secreted

Background

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399