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DDR1 antibody

Anti-DDR1 antibody used in Western Blot (WB). GTX25508
Anti-DDR1 antibody used in Western Blot (WB). GTX25508
Anti-DDR1 antibody used in Flow cytometry (FACS). GTX25508
Anti-DDR1 antibody used in Western Blot (WB). GTX25508
Anti-DDR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX25508

Cat. No. GTX25508

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Rat
Package
400 μl ($399)
See all DDR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:25
Not tested in other applications.

Calculated MW

101 kDa. ( Note )

Positive Control

Placenta lysate.

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human DDR1.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

RRID

AB_380569

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

discoidin domain receptor tyrosine kinase 1 , CAK , CD167 , DDR , EDDR1 , HGK2 , MCK10 , NEP , NTRK4 , PTK3 , PTK3A , RTK6 , TRKE

Background

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-DDR1 antibody used in Western Blot (WB). GTX25508

GTX25508 WB Image

WB analysis of rat brain lysate using GTX25508 DDR1 antibody.
Loading : 20 μg per lane
Dilution : 1:2000

Anti-DDR1 antibody used in Western Blot (WB). GTX25508

GTX25508 WB Image

WB analysis of human placenta lysate using GTX25508 DDR1 antibody.

Anti-DDR1 antibody used in Flow cytometry (FACS). GTX25508

GTX25508 FACS Image

FACS analysis of MCF-7 cells using GTX25508 DDR1 antibody.
Green : DDR1
Blue : Isotype control
Fixation : 2% paraformaldehyde (PFA) (10 min)
Permeabilization : 90% methanol (10 min)
Dilution : 1:25

Anti-DDR1 antibody used in Western Blot (WB). GTX25508

GTX25508 WB Image

WB analysis of MCF-7 whole cell lysate using GTX25508 DDR1 antibody.
Loading : 20 μg per lane
Dilution : 1:2000

Anti-DDR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX25508

GTX25508 IHC-P Image

IHC-P analysis of human kidney tissue using GTX25508 DDR1 antibody.

REFERENCE

Application Reference

Romayor I et al. Cell Adh Migr 2020; 14 (1) : 69-81 Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells.
Application : FACS
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399