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DPP6 antibody

Anti-DPP6 antibody used in Western Blot (WB). GTX54792
Anti-DPP6 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54792
Anti-DPP6 antibody used in Western Blot (WB). GTX54792
Anti-DPP6 antibody used in IHC (Free Floating) (IHC (Free Floating)). GTX54792

Cat. No. GTX54792

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr, IHC (Free Floating)

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all DPP6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
IHC (Free Floating) Assay dependent
Not tested in other applications.

Calculated MW

98 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide (C)KKHEDESEAWLHR, corresponding to amino acid residues 414-426 (Extracellular, C-terminus) of human DPP6 (Accession  : P42658).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dipeptidyl peptidase like 6 , DPL1 , DPPX , MRD33 , VF2

Cellular Localization

Cell membrane

Background

This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES

Anti-DPP6 antibody used in Western Blot (WB). GTX54792

GTX54792 WB Image

IHC-Frfl (free floating) analysis of rat hippocampus tissue using GTX54792 DPP6 antibody. Cell nuclei are stained with DAPI (blue).
Panel A : DPP6 (green) is expressed in the CA3 rat hippocampal region.
Panel B : KV4.2 (red) is expressed in the same region.
Panel C : Merge of the two images demonstrates partial colocalization in neurons of the CA3 region (arrows).
Dilution : 1:1000

Anti-DPP6 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54792

GTX54792 IHC-Fr Image

WB analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4)  brain lysates using GTX54792 DPP6 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-DPP6 antibody used in Western Blot (WB). GTX54792

GTX54792 WB Image

WB analysis of SH-SY5Y cell lysates using GTX54792 DPP6 antibody preincubated with or without immunogen peptide.
Dilution : 1:500

Anti-DPP6 antibody used in IHC (Free Floating) (IHC (Free Floating)). GTX54792

GTX54792 IHC (Free Floating) Image

IHC-Fr analysis of mouse hippocampus tissue using GTX54792 DPP6 antibody. Staining in the hippocampal CA3 region appears in interneurons (arrows). DAPI is used to stain nuclei (blue).
Dilution : 1:400

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639