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DYNLL1 antibody [AT13C9]

Anti-DYNLL1 antibody [AT13C9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57639
Anti-DYNLL1 antibody [AT13C9] used in Western Blot (WB). GTX57639

Cat. No. GTX57639

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AT13C9

Isotype

 IgG2b

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all DYNLL1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

10 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 10% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The clone AT13C9 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DYNLL protein.

Purification

Protein A Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynein light chain LC8-type 1 , DLC1 , DLC8 , DNCL1 , DNCLC1 , DYNLL1 , LC8 , LC8a , PIN , dynein light chain LC8type 1 , hdlc1

Cellular Localization

Cytoplasm,Cytoskeleton,Nucleus,Mitochondrion

Background

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DYNLL1 antibody [AT13C9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57639

GTX57639 ICC/IF Image

ICC/IF analysis of A549 cells using GTX57639 DYNLL1 antibody.
Blue: DAPI
Green: Primary antibody
Dilution: 1:100

Anti-DYNLL1 antibody [AT13C9] used in Western Blot (WB). GTX57639

GTX57639 WB Image

WB analysis of various samples using GTX57639 DYNLL1 antibody.
Lane 1 : HeLa whole cell lysate
Lane 2 : A549 whole cell lysate
Lane 3 : 293T whole cell lysate
Lane 4 : HepG2 whole cell lysate
Loading : 40 μg
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399