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DcR1 antibody [AT1E12]

Anti-DcR1 antibody [AT1E12] used in Western Blot (WB). GTX57733
Anti-DcR1 antibody [AT1E12] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57733

Cat. No. GTX57733

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AT1E12

Isotype

 IgG1

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all DcR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 10% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The clone AT1E12 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TNFRSF12C protein.

Purification

Protein A Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 10c , CD263 , DCR1 , DCR1TNFR , LIT , TNFRSF10C , TRAILR3 , TRID , DcR1 , TRAIL-R3

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8794 TNFRSF10C
  • UniProt: O14798 TNFRSF10C

Research Area

DATA IMAGES

Anti-DcR1 antibody [AT1E12] used in Western Blot (WB). GTX57733

GTX57733 WB Image

WB analysis of Mouse liver tissue lysate using GTX57733 DcR1 antibody.
Loading : 40 μg
Dilution : 1:1000

Anti-DcR1 antibody [AT1E12] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57733

GTX57733 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX57733 DcR1 antibody.
Blue: DAPI
Green: Primary antibody
Dilution: 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399