APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
3 - 6 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Zebrafish, Bovine, Cat, Dog, Hamster, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Lizard, Marmoset, Opossum, Orangutan, Panda, Shrew, Turkey, Xenopus, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human S1PR1 / EDG1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_424867
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
sphingosine-1-phosphate receptor 1 , CD363 , CHEDG1 , D1S3362 , ECGF1 , EDG1 , S1P1 , S1PR1 , sphingosine1phosphate receptor 1
Cellular Localization
Cell membrane,Endosome,Membrane raft
Background
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Database
Research Area
DATA IMAGES
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GTX77919 IHC-P Image
IHC-P analysis of human, vascular endothelium tissue using GTX77919 EDG1 antibody.
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GTX77919 IHC-P Image
IHC-P analysis of human, placenta tissue using GTX77919 EDG1 antibody.
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REFERENCE
REVIEW
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