Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide: SYICQSVDYSNNVHE, corresponding to Internal sequence amino acids 107-121 of Human ELOVL4.
Immunogen affinity purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Elovl Fatty Acid Elongase 4,Admd,Ct118,Isqmr,Sca34,Stgd2,Stgd3,Elovl4
Endoplasmic reticulum membrane; Multi-pass membrane protein
Mutations in ELOVL4, a 38-39 kDa protein photoreceptor cell-specific protein involved in the elongation of very long chain fatty acids, are linked with Stargardt-like macular dystrophy, autosomal dominant macular dystrophy, and other pattern dystrophy. The ELOVL4 gene is homologous to mammalian and yeast enzymes involved in the membrane-bound fatty acid chain elongation system. It has been suggested that alterations in the biosynthesis of fatty acids may be implicated in the pathogenesis of inherited macular degeneration.