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Emerin antibody

Anti-Emerin antibody used in Western Blot (WB). GTX85058
Anti-Emerin antibody used in IHC (Paraffin sections) (IHC-P). GTX85058
Anti-Emerin antibody used in IHC (Paraffin sections) (IHC-P). GTX85058

Cat. No. GTX85058

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Emerin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

Positive Control

Human Skeletal Muscle Tissue Lysate

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Emerin antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Emerin.The immunogen is located within the first 50 amino acids of Emerin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

emerin , EDMD , LEMD5 , STA

Cellular Localization

Nucleus inner membrane,Nucleus outer membrane

Background

Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family that includes proteins such as LAP2 and MAN1. Each family member, including Emerin, has an ~40 amino acid LEM-domains that binds barrier-to-autointegration (BANF1), a conserved chromatin protein that also serves as a host cell component of retroviral integration complexes, including that of HIV. Emerin is anchored at the inner membrane of the nuclear envelope where it binds to nuclear intermediate filaments that are formed by lamin proteins. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.

Database

Research Area

DATA IMAGES

Anti-Emerin antibody used in Western Blot (WB). GTX85058

GTX85058 WB Image

WB analysis of human skeletal muscle tissue lysate using GTX85058 Emerin antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-Emerin antibody used in IHC (Paraffin sections) (IHC-P). GTX85058

GTX85058 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX85058 Emerin antibody.
Working concentration : 2.5 μg/ml

Anti-Emerin antibody used in IHC (Paraffin sections) (IHC-P). GTX85058

GTX85058 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX85058 Emerin antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399