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FANCL antibody

Anti-FANCL antibody used in Western Blot (WB). GTX64576
Anti-FANCL antibody used in IHC (Paraffin sections) (IHC-P). GTX64576
Anti-FANCL antibody used in IHC (Paraffin sections) (IHC-P). GTX64576

Cat. No. GTX64576

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all FANCL products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200 - 1:2000
IHC-P 1:20 - 1:200
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCL (NP_060532.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FA complementation group L , FAAP43 , PHF9 , POG

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a ubiquitin ligase that is a member of the Fanconi anemia complementation group (FANC). Members of this group are related by their assembly into a common nuclear protein complex rather than by sequence similarity. This gene encodes the protein for complementation group L that mediates monoubiquitination of FANCD2 as well as FANCI. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2018]

Database

Research Area

DATA IMAGES

Anti-FANCL antibody used in Western Blot (WB). GTX64576

GTX64576 WB Image

WB analysis of mouse thymus tissue lysate using GTX64576 FANCL antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-FANCL antibody used in IHC (Paraffin sections) (IHC-P). GTX64576

GTX64576 IHC-P Image

IHC-P analysis of human esophagus tissue using GTX64576 FANCL antibody.
Dilution : 1:100

Anti-FANCL antibody used in IHC (Paraffin sections) (IHC-P). GTX64576

GTX64576 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX64576 FANCL antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399