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FAT2 antibody [8C5]

Anti-FAT2 antibody [8C5] used in IHC (Paraffin sections) (IHC-P). GTX34721
Anti-FAT2 antibody [8C5] used in IHC (Paraffin sections) (IHC-P). GTX34721

Cat. No. GTX34721

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8C5

Isotype

 IgG1

Application

 ICC/IF, IHC-P, FACS

Reactivity

 Human
Package
100 μg ($529)
See all FAT2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1-2μg/ml
IHC-P 1-2μg/ml for 30 min at RT
FACS 1-2μg/10⁶ cells

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

479 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human FAT2 fusion protein.

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CDHF8 , CDHR9 , FAT atypical cadherin 2 , FAT2 , HFAT2 , MEGF1

Cellular Localization

Cell membrane,Cell junction,Nucleus

Background

This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-FAT2 antibody [8C5] used in IHC (Paraffin sections) (IHC-P). GTX34721

GTX34721 IHC-P Image

IHC-P analysis of human cervical carcinoma tissue using GTX34721 FAT2 antibody [8C5].

Anti-FAT2 antibody [8C5] used in IHC (Paraffin sections) (IHC-P). GTX34721

GTX34721 IHC-P Image

IHC-P analysis of human bladder carcinoma tissue using GTX34721 FAT2 antibody [8C5].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529