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FMRP antibody [4G9]

Anti-FMRP antibody [4G9] used in IHC (Paraffin sections) (IHC-P). GTX83130
Anti-FMRP antibody [4G9] used in Western Blot (WB). GTX83130
Anti-FMRP antibody [4G9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83130

Cat. No. GTX83130

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4G9

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all FMRP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human FMRP expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fragile X mental retardation 1 , FMRP , FRAXA , POF , POF1

Cellular Localization

Nucleus,Cytoplasm,Cell projection, dendrite,Cell junction, synapse,Cell membrane,Nucleolus

Background

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-FMRP antibody [4G9] used in IHC (Paraffin sections) (IHC-P). GTX83130

GTX83130 IHC-P Image

IHC-P analysis of human brain tissue using GTX83130 FMRP antibody [4G9].

Anti-FMRP antibody [4G9] used in Western Blot (WB). GTX83130

GTX83130 WB Image

WB analysis of Jurkat (1) and K562 (2) cell lysate using GTX83130 FMRP antibody [4G9].

Anti-FMRP antibody [4G9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83130

GTX83130 ICC/IF Image

ICC/IF analysis of NIH3T3 cells using GTX83130 FMRP antibody [4G9].
Green : FMRP
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399