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FTO antibody [5-2H10]

Anti-FTO antibody [5-2H10] used in Western Blot (WB). GTX82693

Cat. No. GTX82693

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5-2H10

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat
Package
100 μl ($499)
See all FTO products

APPLICATION

Application Note

Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FTO alpha-ketoglutarate dependent dioxygenase , ALKBH9 , BMIQ14 , GDFD

Cellular Localization

Nucleus , Nucleus speckle , Cytoplasm

Background

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-FTO antibody [5-2H10] used in Western Blot (WB). GTX82693

GTX82693 WB Image

Western blot of rat testes lysate showing specific immunolabeling of the ~58k Fto protein using Fatso antibody [5-2H10] (GTX 82693).

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 499