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GABA A Receptor alpha 6 antibody [HL1669]

Recombinant antibody
Anti-GABA A Receptor alpha 6 antibody [HL1669] used in Western Blot (WB). GTX637268
Anti-GABA A Receptor alpha 6 antibody [HL1669] used in Western Blot (WB). GTX637268
Anti-GABA A Receptor alpha 6 antibody [HL1669] used in Western Blot (WB). GTX637268

Cat. No. GTX637268

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL1669

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all GABA A Receptor alpha 6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Product Note

This antibody was raised against human GABA A Receptor alpha 6 Intracellular domain.

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human GABA A Receptor alpha 6. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

gamma-aminobutyric acid type A receptor alpha6 subunit

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GABA A Receptor alpha 6 antibody [HL1669] used in Western Blot (WB). GTX637268

GTX637268 WB Image

Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 6 antibody [HL1669] (GTX637268) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-GABA A Receptor alpha 6 antibody [HL1669] used in Western Blot (WB). GTX637268

GTX637268 WB Image

Whole cell extract (30 Âμg) was separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 6 antibody [HL1669] (GTX637268) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-GABA A Receptor alpha 6 antibody [HL1669] used in Western Blot (WB). GTX637268

GTX637268 WB Image

Human tissue extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 6 antibody [HL1669] (GTX637268) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations