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GABA A Receptor beta 3 (phospho Ser408/409) antibody

Anti-GABA A Receptor beta 3 (phospho Ser408/409) antibody used in Western Blot (WB). GTX82680

Cat. No. GTX82680

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Rat
Package
100 μl ($499)
See all GABA A Receptor beta 3 products

APPLICATION

Application Note

Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

54 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser408/409 conjugated to KLH

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_11172742

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

gamma-aminobutyric acid type A receptor beta 3 subunit

Cellular Localization

Cell membrane

Background

beta 3 subunit, with alpha subunits forms active GABA-A receptors [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-GABA A Receptor beta 3 (phospho Ser408/409) antibody used in Western Blot (WB). GTX82680

GTX82680 WB Image

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~53k GABAA beta 3 protein phosphorylated at Ser 408/409 (control) using GABAA Receptor, beta 3 (phospho Ser408/409) antibody (GTX82680). Immunolabeling is blocked by the phospho-peptide (peptide) used as antigen.

REFERENCE

Application Reference

Huang L et al. Eur J Pharmacol 2017; 797 : 134-142 Rho-kinase inhibitor prevents acute injury against transient focal cerebral ischemia by enhancing the expression and function of GABA receptors in rats.
Application : WB
Reactivity : Rat
Huang L et al. Neuroscience 2014; 277C : 383-391 Long-term inhibition of Rho-kinase restores the LTP impaired in chronic forebrain ischemia rats by regulating GABAA and GABAB receptors.
Application : WB
Reactivity : Rat
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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 499