GATM antibody [N3C3]

Name: GATM antibody [N3C3]
Brand: GeneTex
SKU: GTX114423
Price: 399.00 USD
Rating: 4 (1 reviews)

Anti-GATM antibody [N3C3] used in Western Blot (WB). GTX114423

Cat. No. GTX114423

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Mouse, Zebrafish
Package	100 μl ($399), 25 μl ($169)

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Datasheet
Document

View product citations for antibody GTX114423 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000

Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Positive Control

mouse liver

Predict Reactivity

Rat, Bovine, Dog, Chicken, Pig, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human GATM. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10619565

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glycine amidinotransferase , AGAT , AT , CCDS3

Cellular Localization

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (Potential) , Cytoplasm

Background

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq]

Database

Gene ID: 2628 GATM
UniProt: P50440 GATM

Research Area

DATA IMAGES

GTX114423 WB Image

Sample (30 μg of whole cell lysate)
A: zebrafish eye
10% SDS PAGE
GTX114423 diluted at 1:1000

GTX114423 WB Image

Mouse tissue extract (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with GATM antibody [N3C3] (GTX114423) diluted at 1:500.

REFERENCE

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REVIEW