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GDF8 / Myostatin antibody

Anti-GDF8 / Myostatin antibody used in Western Blot (WB). GTX03461
Anti-GDF8 / Myostatin antibody used in IHC (Paraffin sections) (IHC-P). GTX03461
Anti-GDF8 / Myostatin antibody used in Western Blot (WB). GTX03461
Anti-GDF8 / Myostatin antibody used in Western Blot (WB). GTX03461

Cat. No. GTX03461

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat, Pig
Package
100 μl ($399)
See all GDF8 / Myostatin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P 1:100-1:500
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Predict Reactivity

Sheep, Bovine, Chicken, Horse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 1% BSA, 50% Glycerol

Preservative

0.03% Proclin300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human GDF8 (281-375).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

myostatin , GDF8 , MSLHP

Cellular Localization

Secreted

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-GDF8 / Myostatin antibody used in Western Blot (WB). GTX03461

GTX03461 WB Image

WB analysis of various sample lysates using GTX03461 GDF8 / Myostatin antibody.
Lanes 1 and 2 : human muscle tissue lysate
Lanes 3 and 4 : C2C12 whole cell lysate
Dilution : 1:1000

Anti-GDF8 / Myostatin antibody used in IHC (Paraffin sections) (IHC-P). GTX03461

GTX03461 IHC-P Image

IHC-P analysis of mouse small intestine tissue using GTX03461 GDF8 / Myostatin antibody.
Dilution : 1:200

Anti-GDF8 / Myostatin antibody used in Western Blot (WB). GTX03461

GTX03461 WB Image

WB analysis of various sample lysates using GTX03461 GDF8 / Myostatin antibody.
Lane 1 : Mouse Muscle tissue lysate
Lane 2 : Rat Muscle tissue lysate
Lane 3 : Rat Tongue tissue lysate
Dilution : 1:1000

Anti-GDF8 / Myostatin antibody used in Western Blot (WB). GTX03461

GTX03461 WB Image

WB analysis of mouse skeletal muscle lysate using GTX03461 GDF8 / Myostatin antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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Package List Price ($)
$ 399