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GLP1 antibody [10]

Anti-GLP1 antibody [10] used in ELISA (ELISA). GTX60952

Cat. No. GTX60952

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10

Isotype

 IgG2a

Application

 WB, ELISA

Reactivity

 Human
Package
100 μl ($569)
See all GLP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

Product Note

This antibody binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4.

PROPERTIES

Form

Liquid

Buffer

10mM Phosphate, 500mM NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic GLP-1(7-17)

Purification

Protein-A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glucagon , GLP-1 , GLP1 , GLP2 , GRPP

Cellular Localization

Secreted

Background

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GLP1 antibody [10] used in ELISA (ELISA). GTX60952

GTX60952 ELISA Image

It is possible to measure intact exendin-4 by a sandwich ELISA which is not subject to interference from GLP-1 or other glucagon-related peptides that may be present. GTX60952 is used as capture antibody in combination with a biotinylated detection antibody GTX60993-02.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 569