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GM-CSF antibody [MP1-22E9]

Cat. No. GTX13788

Reference 3

Host

 Rat

Clonality

 Monoclonal

Clone Name

 MP1-22E9

Isotype

 IgG2a

Application

 WB, IHC-Fr, FACS, ELISA, ELISPOT, Neutralizing/Inhibition

Reactivity

 Mouse
Package
100 μg ($399)
See all GM-CSF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
ELISA Assay dependent
ELISPOT Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

WB
Detects less than 100ng protein under reducing conditions
Not tested in other applications.

Calculated MW

16 kDa. ( Note )

Positive Control

Recombinant mouse GM-CSF

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse GM-CSF

Purification

Protein G purified
This antibody is affinity purified.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

colony stimulating factor 2 , CSF , GMCSF

Cellular Localization

Secreted

Background

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

L Vaillant et al. Helicobacter 2022; 27 (2):e12875 GM-CSF is key in the efficacy of vaccine-induced reduction of Helicobacter pylori infection
Application : FACS
D Regan-Komito et al. Nat Commun 2020; 11 (1):155 GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis
Application : FACS
AD Cook et al. Arthritis Res Ther 2012; 14 (5):R199 Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399