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GRK2 antibody

KO/KD
Anti-GRK2 antibody used in Western Blot (WB). GTX35230
Anti-GRK2 antibody used in Western Blot (WB). GTX35230
Anti-GRK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35230
Anti-GRK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35230
Anti-GRK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35230

Cat. No. GTX35230

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all GRK2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

G protein-coupled receptor kinase 2 , ADRBK1 , BARK1 , BETA-ARK1

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES

Anti-GRK2 antibody used in Western Blot (WB). GTX35230

GTX35230 WB Image

KO/KD

WB analysis of normal (control) and GRK2 knockout (KO) 293T cell lysates using GTX35230 GRK2 antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-GRK2 antibody used in Western Blot (WB). GTX35230

GTX35230 WB Image

WB analysis of various sample lysates using GTX35230 GRK2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-GRK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35230

GTX35230 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX35230 GRK2 antibody.
Dilution : 1:200

Anti-GRK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35230

GTX35230 IHC-P Image

IHC-P analysis of rat brain tissue using GTX35230 GRK2 antibody.
Dilution : 1:200

Anti-GRK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35230

GTX35230 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX35230 GRK2 antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399