APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:1000 |
Not tested in other applications.
Calculated MW
Product Note
The N-terminal 18 aa signal peptide is cleaved during GluR1 maturation. The Ser831 of mature GluR1 is equivalent to Ser849 of uncleaved GluR1.
Predict Reactivity
Human, Rat(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human GluR1 around the phosphorylation site of serine 849 (Q-Q-Sp-I-N ).
Purification
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum
Conjugation
Unconjugated
RRID
AB_11170696
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
GLUH1,GLUR1,GLURA,GRIA1,GluA1,HBGR1,glutamate ionotropic receptor AMPA type subunit 1,GluR1,Glutamate Receptor 1
Cellular Localization
Cell membrane,Endoplasmic reticulum membrane,Cell junction,Synapse,Postsynaptic cell membrane,Postsynaptic density,Cell projection,Dendrite,Dendritic spine
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX79065 WB Image
WB analysis of mouse brain tissue lysate using GTX79065 GluR1 (phospho Ser831) antibody (Lane 3 and 4) and GluR1 antibody (Lane 1 and 2).
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REFERENCE
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REVIEW
There are currently no reviews for GluR1 (phospho Ser831) antibody (GTX79065). Be the first to share your experience with this product.
