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GluR4 antibody

Anti-GluR4 antibody used in Western Blot (WB). GTX57743
Anti-GluR4 antibody used in IHC (Frozen sections) (IHC-Fr). GTX57743

Cat. No. GTX57743

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all GluR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

101 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.6 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)KLMDRWKKLDQRE, corresponding to amino acid residues 274-286 of rat GluR4 (Accession P19493). Extracellular, N-terminus.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glutamate ionotropic receptor AMPA type subunit 4 , GluA4 , GluR-D , GluR4

Cellular Localization

Cell membrane; Multi-pass membrane protein,Cell projection, dendrite

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GluR4 antibody used in Western Blot (WB). GTX57743

GTX57743 WB Image

WB analysis of rat brain membranes (Lanes 1 and 3) and mouse brain (Lanes 2 and 4) lysates using GTX57743 GluR4 antibody.
Lane 1 and 2 : Primary antibody
Lane 3 and 4 : Primary antibody preincubated with the control peptide antigen
Dilution : 1:200

Anti-GluR4 antibody used in IHC (Frozen sections) (IHC-Fr). GTX57743

GTX57743 IHC-Fr Image

IHC-Fr analysis of rat dorsal root ganglion (DRG) tissue using GTX57743 GluR4 antibody.
Red : Primary antibody
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639