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Glucokinase antibody [4G6]

Anti-Glucokinase antibody [4G6] used in Western Blot (WB). GTX60474
Anti-Glucokinase antibody [4G6] used in Western Blot (WB). GTX60474
Anti-Glucokinase antibody [4G6] used in ELISA (ELISA). GTX60474

Cat. No. GTX60474

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4G6

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human
Package
100 μl ($409)
See all Glucokinase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ELISA 1/10000
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human Glucokinase expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glucokinase , FGQTL3 , GK , GLK , HHF3 , HK4 , HKIV , HXKP , LGLK , MODY2

Cellular Localization

Cytoplasm,Nucleus

Background

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009]

Database

Research Area

DATA IMAGES

Anti-Glucokinase antibody [4G6] used in Western Blot (WB). GTX60474

GTX60474 WB Image

WB analysis of human GCK (AA: 1-198) recombinant protein using GTX60474 Glucokinase antibody [4G6].

Anti-Glucokinase antibody [4G6] used in Western Blot (WB). GTX60474

GTX60474 WB Image

WB analysis of HEK293 (1) and Glucokinase-hIgGFc transfected HEK293 (2) cell lysate using GTX60474 Glucokinase antibody [4G6].

Anti-Glucokinase antibody [4G6] used in ELISA (ELISA). GTX60474

GTX60474 ELISA Image

ELISA analysis of antigen using GTX60474 Glucokinase antibody [4G6].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409