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Granzyme B antibody [CLB-GB11]

Anti-Granzyme B antibody [CLB-GB11] used in Flow cytometry (FACS). GTX80192

Cat. No. GTX80192

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CLB-GB11

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Primate
Package
100 μg ($339)
See all Granzyme B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

TBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human NK cell line YT-INDY-derived granzyme B

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C11 , CCPI , CGL1 , CSPB , CTLA1 , CTSGL1 , GZMB , HLP , SECT , granzyme B , Granzyme B

Cellular Localization

Cytoplasmic granule

Background

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-Granzyme B antibody [CLB-GB11] used in Flow cytometry (FACS). GTX80192

GTX80192 FACS Image

Flow cytometry analysis of human CD8+ peripheral blood cells with anti-human granzyme B: PE (GTX80192)

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 339