GeneTex

  • Country / Location Selection

United States (US)

Granzyme B antibody [GZMB/2403]

Anti-Granzyme B antibody [GZMB/2403] used in Protein Array (Protein Array). GTX18107

Cat. No. GTX18107

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 GZMB/2403

Isotype

 IgG2b

Application

 ELISA, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all Granzyme B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA 1-5μg/ml (for coating)
Protein Array Assay dependent

Note :

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human GZMB protein (around aa 73-187) (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C11 , CCPI , CGL1 , CSPB , CTLA1 , CTSGL1 , GZMB , HLP , SECT , granzyme B , Granzyme B

Cellular Localization

Cytoplasmic granule

Background

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-Granzyme B antibody [GZMB/2403] used in Protein Array (Protein Array). GTX18107

GTX18107 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using Granzyme B Mouse Monoclonal Antibody (GZMB/2403). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

There are currently no references for Granzyme B antibody [GZMB/2403] (GTX18107). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Granzyme B antibody [GZMB/2403] (GTX18107). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529