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HEXA antibody [3F10]

Anti-HEXA antibody [3F10] used in Western Blot (WB). GTX60574
Anti-HEXA antibody [3F10] used in ELISA (ELISA). GTX60574
Anti-HEXA antibody [3F10] used in Flow cytometry (FACS). GTX60574

Cat. No. GTX60574

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3F10

Isotype

 IgG2b

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μg ($409)
See all HEXA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human HEXA expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

hexosaminidase subunit alpha , TSD

Cellular Localization

Lysosome

Background

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009]

Database

Research Area

DATA IMAGES

Anti-HEXA antibody [3F10] used in Western Blot (WB). GTX60574

GTX60574 WB Image

WB analysis of L1210 (1), and HL7702 (2) cell lysate using GTX60574 HEXA antibody [3F10].

Anti-HEXA antibody [3F10] used in ELISA (ELISA). GTX60574

GTX60574 ELISA Image

ELISA analysis of antigen using GTX60574 HEXA antibody [3F10].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-HEXA antibody [3F10] used in Flow cytometry (FACS). GTX60574

GTX60574 FACS Image

FACS analysis of HeLa cells using GTX60574 HEXA antibody [3F10].
Green : HEXA
Red : negative control

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409