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IKK gamma antibody

Cat. No. GTX27890

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μg ($479)
See all IKK gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1,000
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Product Note

This antibody recognizes IKKγ (52 kD). No cross-reactivity with IKKα, IKKβ or IKKε.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to aa 400-416 of human IKKγ. This sequence is identical to that of mouse.

Purification

Purified by DEAE chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AMCBX1 , FIP3 , Fip3p , IKBKG , IKKAP1 , IKKG , IKKgamma , IMD33 , IP , IP1 , IP2 , IPD2 , NEMO , ZC2HC9 , inhibitor of kappa light polypeptide gene enhancer in Bcells, kinase gamma , IKK gamma , inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 479