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IL10 Receptor alpha antibody [1B1.3a] (Azide free)

Cat. No. GTX41726

Reference 1

Host

 Rat

Clonality

 Monoclonal

Clone Name

 1B1.3a

Isotype

 IgG1

Application

 FACS, Neutralizing/Inhibition

Reactivity

 Mouse
Package
500 μg ($529)
See all IL10 Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 1/10-1/100
Neutralizing/Inhibition Assay dependent

Note :

FACS
Due to low expression of IL10 Receptor alpha, sensitive staining techniques may be required.Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Neutralizing/Inhibition
Rat anti Mouse CDw210a antibody, clone 1B1.3a is reported to neutralize the effects of IL-10 (Asseman et al. 1997).
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

Product Note

The epitope recognized by this antibody has been localised to the ligand binding domain within the extracellular region.Clone 1B1.3a is reported to neutralize the effects of IL-10 (Asseman et al. 1997).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Purified recombinant extracellular region of mouse CDw210a.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 10 receptor, alpha , AW553859 , CDw210 , CDw210a , IL-10R1 , IL-10RA , Il10r , mIL-10R

Cellular Localization

Cell membrane , Cytoplasm

Database

Research Area

REFERENCE

Clone Reference

Gaupp S et al. Am J Pathol 2008; 173 (1):119-29 Amelioration of experimental autoimmune encephalomyelitis in IL-4Ralpha-/- mice implicates compensatory up-regulation of Th2-type cytokines.
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 529
Custom Conjugations