GeneTex

  • Country / Location Selection

United States (US)

IL17 Receptor alpha antibody

Anti-IL17 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX16598
Anti-IL17 Receptor alpha antibody used in Western Blot (WB). GTX16598
Anti-IL17 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX16598
Anti-IL17 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX16598

Cat. No. GTX16598

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($419)
See all IL17 Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

Positive Control

A20 Cell Lysate(GTX27180)

Product Note

Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA.The immunogen is located within amino acids 150 - 200 of IL-17RA.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887540

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 17 receptor A , CANDF5 , CD217 , CDw217 , IL-17RA , IL17R , IMD51 , hIL-17R

Background

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-IL17 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX16598

GTX16598 IHC-P Image

IHC-P analysis of human spleen tissue using GTX16598 IL17 Receptor alpha antibody.
Working concentration : 2.5 μg/ml

Anti-IL17 Receptor alpha antibody used in Western Blot (WB). GTX16598

GTX16598 WB Image

WB analysis of A-20 cell lysate using GTX16598 IL17 Receptor alpha antibody.
Working concentration : 1 μg/ml

Anti-IL17 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX16598

GTX16598 IHC-P Image

IHC-P analysis of human spleen tissue using GTX16598 IL17 Receptor alpha antibody.
Working concentration : 20 μg/ml

Anti-IL17 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX16598

GTX16598 IHC-P Image

IHC-P analysis of human spleen tissue using GTX16598 IL17 Receptor alpha antibody.
Working concentration : 2.5 μg/ml

REFERENCE

Application Reference

Farouk S et al. PLoS One 2018; 13 (10) : e0206130 Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl4-induced rat liver fibrosis.
Application : IHC-P
Reactivity : Rat
Submit a Reference

REVIEW

There are currently no reviews for IL17 Receptor alpha antibody (GTX16598). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419