GeneTex

  • Country / Location Selection

United States (US)

IL6 antibody [5E1]

Cat. No. GTX54414

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5E1

Isotype

 IgG1

Application

 WB, IP, ELISA, Functional Assay

Reactivity

 Human, Cynomolgus monkey, Rhesus Monkey
Package
100 μg ($399)
See all IL6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IP Assay dependent
ELISA Assay dependent
Functional Assay Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Product Note

The antibody inhibits the biological activity of human native and recombinant IL-6 as determined with the B9 cell bioassay.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BSF2,CDF,HGF,HSF,IFNB2,IFNbeta2,IL6,interleukin 6,Interleukin 6

Cellular Localization

Secreted

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Database

Research Area

REFERENCE

There are currently no references for IL6 antibody [5E1] (GTX54414). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for IL6 antibody [5E1] (GTX54414). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 399