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ITGB3BP antibody

Anti-ITGB3BP antibody used in Western Blot (WB). GTX03692

Cat. No. GTX03692

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($399)
See all ITGB3BP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
Not tested in other applications.

Calculated MW

20 kDa. ( Note )

Predict Reactivity

Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.4, 150mM NaCl, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human ITGB3BP(Accession Q13352), corresponding to amino acid residues S49-S71.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 3 binding protein , CENP-R , CENPR , HSU37139 , NRIF3 , TAP20

Cellular Localization

Cytoplasm

Background

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-ITGB3BP antibody used in Western Blot (WB). GTX03692

GTX03692 WB Image

WB analysis of A431 cell lysates using GTX03692 ITGB3BP antibody. The lane on the left was treated with antigen-specific peptide.
Loading : 25 μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399