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IVNS1ABP antibody

Anti-IVNS1ABP antibody used in Western Blot (WB). GTX118817
Anti-IVNS1ABP antibody used in IHC (Paraffin sections) (IHC-P). GTX118817
Anti-IVNS1ABP antibody used in IHC (Paraffin sections) (IHC-P). GTX118817

Cat. No. GTX118817

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all IVNS1ABP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Positive Control

U87-MG

Predict Reactivity

Rat, Bovine, Pig, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.57 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11165467

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

influenza virus NS1A binding protein , ARA3 , FLARA3 , HSPC068 , KLHL39 , ND1 , NS-1 , NS1-BP , NS1BP

Cellular Localization

Cytoplasm , cytoskeleton , Nucleus , nucleoplasm

Background

Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Database

Research Area

DATA IMAGES

Anti-IVNS1ABP antibody used in Western Blot (WB). GTX118817

GTX118817 WB Image

Sample (30 ug of whole cell lysate)
A: U87-MG
7.5% SDS PAGE
GTX118817 diluted at 1:1000

Anti-IVNS1ABP antibody used in IHC (Paraffin sections) (IHC-P). GTX118817

GTX118817 IHC-P Image

Immunohistochemical analysis of paraffin-embedded mouse muscle, using IVNS1ABP(GTX118817) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-IVNS1ABP antibody used in IHC (Paraffin sections) (IHC-P). GTX118817

GTX118817 IHC-P Image

IVNS1ABP antibody detects IVNS1ABP protein at cytoplasm in mouse kidney by immunohistochemical analysis.
Sample: Paraffin-embedded mouse kidney.
IVNS1ABP antibody (GTX118817) diluted at 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

Application Reference

Zhang Z et al. Gastric Cancer 2020; 23 (3) : 437-448 CircDUSP16 promotes the tumorigenesis and invasion of gastric cancer by sponging miR-145-5p.
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169