APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Note :
Sandwich ELISA
Capture : GTX28302, Detection : GTX28303
|
Not tested in other applications.
Calculated MW
Product Note
Clone 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. These antibodies react with insulin/proinsulin but not react with free C-peptide.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified human insulin.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Cellular Localization
Secreted
Background
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Database
Research Area
REFERENCE
There are currently no references for Insulin antibody [D4B8] (GTX28303). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Insulin antibody [D4B8] (GTX28303). Be the first to share your experience with this product.