GeneTex

  • Country / Location Selection

United States (US)

Integrin alpha 4 antibody [PS/2] (Low endotoxin, azide free)

Cat. No. GTX41951

Reference 3

Host

 Rat

Clonality

 Monoclonal

Clone Name

 PS/2

Isotype

 IgG2b

Application

 FACS, IP, Neutralizing/Inhibition

Reactivity

 Human, Mouse
Package
200 μg ($619)
See all Integrin alpha 4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
IP Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
Clone PS/2 has also been reported to block the binding of Integrin alpha 4 to its ligands (Andrew et al. 1994).
Not tested in other applications.

Calculated MW

116 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse P815 mast cells

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/μg (determined by the LAL assay)

Conjugation

Unconjugated

RRID

AB_11169833

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Membrane

Database

Research Area

REFERENCE

Application Reference

Abplanalp WT et al. Diabetes 2016; Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes.
Application : IP
Reactivity : Mouse

Clone Reference

Yousef H et al. Nat Med 2019; 25 (6):988-1000 Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
D P Andrew et al. J Immunol. 1994; 153 (9):3847-61 Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation
Application : Neutralizing/Inhibition
Reactivity : Mouse
Submit a Reference

REVIEW

There are currently no reviews for Integrin alpha 4 antibody [PS/2] (Low endotoxin, azide free) (GTX41951). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 619